Immunology In Biotechnology - Practice Test

[#41] A humanized antibody is one in which the

(A) Heavy and light chains are from human

(B) Heavy chain is from human and light chain is from mouse

(C) Light chain is from human and heavy chain is from mouse

(D) CDRs are from mouse, and the rest is from human

Correct Answer

(D) CDRs are from mouse, and the rest is from human

[#42] Match the autoimmune diseases in Group I with the corresponding primarily affected organ in Group II . Group I Group II P. Hashimoto's disease 1. Brain Q. Juvenile diabetes 2. Pancreas R. Multiple sclerosis 3. Skeletal muscle S. Myasthenia gravis 4. Thyroid

(A) P-1, Q-2, R-3, S-4

(B) P-3, Q-1, R-2, S-4

(C) P-4, Q-2, R-1, S-3

(D) P-1, Q-2, R-4, S-3

Correct Answer

(C) P-4, Q-2, R-1, S-3

[#43] Which one of the following statements is true with regard to processing and presentation of protein antigens?

(A) In the class II MHC pathway, protein antigens in the cytosol are processed by proteasomes

(B) In the class I MHC pathway, extracellular protein antigens are endocytosed into vesicles and processed

(C) In the class I MHC pathway, transporter associated antigen processing (TAP) protein is required for translocating processed peptides generated in the cytosol

(D) Invariant chain in endoplasmic reticulum is involved in transport of peptides and loading of class I MHC

Correct Answer

(C) In the class I MHC pathway, transporter associated antigen processing (TAP) protein is required for translocating processed peptides generated in the cytosol

[#44] Which of the following cytokines are endogenous pyrogens? P. Tumor necrosis factor α Q. Interleukin 1 R. Transforming growth factor β S. Interleukin 10

(A) P and Q only

(B) P and R only

(C) R and S only

(D) Q and S only

Correct Answer

(A) P and Q only

[#45] B-lymphocytes originate from the bone marrow, whereas T lymphocytes originate from

(A) Thymus

(B) Bone marrow

(C) Spleen

(D) Liver

Correct Answer

(B) Bone marrow

Immunology In Biotechnology - Study Mode

[#41] A humanized antibody is one in which the

Correct Answer

[#42] Match the autoimmune diseases in Group I with the corresponding primarily affected organ in Group II . Group I Group II P. Hashimoto's disease 1. Brain Q. Juvenile diabetes 2. Pancreas R. Multiple sclerosis 3. Skeletal muscle S. Myasthenia gravis 4. Thyroid

Correct Answer

[#43] Which one of the following statements is true with regard to processing and presentation of protein antigens?

Correct Answer

[#44] Which of the following cytokines are endogenous pyrogens? P. Tumor necrosis factor α Q. Interleukin 1 R. Transforming growth factor β S. Interleukin 10

Correct Answer

[#45] B-lymphocytes originate from the bone marrow, whereas T lymphocytes originate from

Correct Answer